Tom Cruise's mother, Mary Lee South, died last week after battling health issues in recent years, multiple outlets report. She was 80 years old. ver the weekend, Tom and his sisters Lee Ann DeVette, 57, Cass Mapother, 55, and Marian Henry, 52, all attended a memorial service for their late mother at a Church of Scientology. Cruise and his mother reportedly shared a close relationship over the years. She once said she was her son’s “greatest audience.”